Neurobiology of addiction koob pdf
An important goal of current neurobiological research on addiction is to understand the neuropharmacological and neuroadaptive mechanisms within specific neurocircuits that mediate the transition between occasional, controlled drug use and the loss of behavioral control Neurobiology of Addiction, by George F. Koob and Michel Le Moal. A number of dramatic breakthroughs in the neurobiology of addiction have occurred in the past 40 years with the support of the National Institute on Drug Abuse (NIDA). Two domains will be highlighted here: the neurocircuitry of addiction and the molecular biology of addiction area907.info by: George Koob. Dr. Koob also is one of the world's authorities on the neurobiology of drug addiction. He has contributed to our understanding of the neurocircuitry associated with the acute reinforcing effects of drugs of abuse and more recently on the neuroadaptations of these reward circuits associated with the transition to area907.info Edition: 1st Edition.